L-Theanine has been shown to lower levels of stress hormones like cortisol. In animal studies, it reduced stress hormone levels both during rest and after exposure to stressful situations. By promoting a state of relaxed alertness, L-Theanine not only helps reduce the impact of stress but may also enhance overall emotional resilience.

L-Theanine doesn’t cause drowsiness like many other sleep supplements. However, studies have found that L-Theanine may shorten the amount of time it takes to fall asleep and can reduce the number of disruptions that occur while sleeping. Better sleep quality has potential to boost mental clarity and mood while awake.

Mitragynine can produce calming effects on the nervous system. This may reduce feelings of nervous tension, promote mental relaxation, and help users feel more grounded during periods of stress.

Mitragynine may help reduce physical discomfort by influencing pain signaling pathways in the brain and body. Research suggests it can modulate how pain is perceived, making everyday aches, muscle tension, or soreness feel less intense.

Magnesium glycinate balances the body's stress response by regulating cortisol (the primary stress hormone). By keeping cortisol levels balanced, magnesium glycinate helps the body recover more efficiently from stressful situations and promotes overall emotional and physical well-being. Magnesium also binds to and activates GABA receptors, which helps to inhibit overactive neural signals, reducing feelings of tension, anxiety, and restlessness, promoting a deeper sense of calm and mental clarity.

Magnesium glycinate supports the production of melatonin, the hormone responsible for regulating the sleep-wake cycle. By naturally enhancing melatonin levels, magnesium glycinate helps signal to the body that it’s time to wind down, making it easier to fall asleep and maintain a consistent sleep schedule.

Vitamin D3 plays an important role in regulating estrogen, testosterone, and progesterone—the key reproductive hormones that influence physical and emotional well-being in both men and women. In women, low D3 levels have been linked to irregular menstrual cycles, PMS symptoms, and hormonal conditions like PCOS. In men, Vitamin D3 plays a role in maintaining testosterone production. Research has shown that low D3 levels are often linked with low testosterone, which can contribute to reduced energy, mood issues, lower libido, and difficulty building or maintaining muscle.

Vitamin D3 plays a crucial role in helping the immune system work efficiently. It activates immune cells like T-cells and macrophages, which detect and destroy harmful pathogens such as viruses and bacteria. Without enough Vitamin D3, these cells may not respond as effectively, which can make the body more vulnerable to infections. Vitamin D3 also helps regulate inflammation, which is a natural part of the immune response but can cause problems when it's too strong or long-lasting. By keeping inflammation in check, D3 supports a balanced immune reaction—strong enough to fight off illness, but not so intense that it leads to unnecessary tissue damage or chronic inflammation.

Vitamin B6 is required for the synthesis of important neurotransmitters, which enable efficient brain signaling. By supporting efficient brain signaling, B6 can help improve attention span, reduce brain fog, and support clearer thinking. Some studies suggest that B6, particularly when combined with B12, may help slow brain aging and reduce the risk of cognitive decline by lowering homocysteine, an amino acid linked to memory loss and brain shrinkage when present in high levels.

Vitamin B6 is essential for converting serotonin into melatonin, the hormone that controls your sleep-wake cycle. Without enough B6, melatonin levels may drop, making it harder to fall asleep and stay asleep.

Vitamin B12 helps maintain the myelin sheath, the protective covering around nerves. This allows for fast and efficient communication between brain cells, which is crucial for memory, learning, and overall brain performance. Some studies suggest that B6, particularly when combined with B12, may help slow brain aging and reduce the risk of cognitive decline by lowering homocysteine, an amino acid linked to memory loss and brain shrinkage when present in high levels.

Vitamin B12 helps maintain a healthy circadian rhythm, which tells your body when to feel alert and when to wind down. This helps you fall asleep and wake up at consistent times. Some studies suggest that B12 supplementation may improve sleep patterns in people with sleep disorders, especially when combined with other supportive nutrients like B6 and magnesium.